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Перегляд Кафедра симуляційних медичних технологій за назвою

Перегляд Кафедра симуляційних медичних технологій за назвою

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Antiseizure effects of cerebellum is mediated via peroxisomal proliferator-activated γ-receptors (PPAR-γ)

Godlevsky, L. S.; Pervak, M. P.; Lyashenko, A. V.; Bidnyuk, K. A. (2021)

Earlier on the model of pentylenetetrazol (PTZ) – induced kindling it was shown that blockade of PPARγ with bisphenol A diglycidyl ether (2,2’-[(1-methylethylidene) bis(4,1- phenyleneoxymethylene)] bis-oxirane (BADGE) ...
Blockade of Н3 histamine receptors facilitates antiseizure action of Pentoxyphilline

Prybolovets, K. O.; Poshyvak, O. B.; Pervak, M. P.; Yehorenko, O. S.; Godlevsky, L. S. (2022)

Considering the important role of inflammation in epilepsy development is reasonable to investigate the effects of combined usage of different modulators of neural inflammation. The work aimed to investigate the effects ...
Cerebellar transcranial direct current stimulation (tDCS) and pitolisant prevented behavioral and neuroinflammatory disturbances in pentylenetetrazol (PTZ) kidnling

Pervak, M. P.; Yehorenko, O. S.; Onuphrienko, O. V.; Varava, S. V.; Litvinenko, M. V.; Godlevsky, L. S. (2024)

The work aimed to investigate behavioral mani‑festations in PTZ‑kindled rats under combined treat‑ment with the histamine H3 receptor inverse agonist pitolisant and mTOR blocker rapamycin. Kindling was produced in Wistar ...
Comparative effectiveness of niacin-oxietilyden-di-phosphonste germanat (MIGU-4) and diazepam upon neuronal loss in the retina of rats with pentylenetetrazol (PTZ)

Al-Nadawi, N.; Pervak, M.; Prybolovets, K.; Arabadzhi, D. R.; Apollonov, D. R. (2023)

Epilepsy is accompanied by neuronal loss, which is observed in the retina as well. The work aimed to study the density of neurons in retina layers of rats with pentylenetetrazol (PTZ)-kindled seizures and compare ...
The correlation of overweight and threatened miscarriage of pregnancy in South Ukrainian women

Nadvorna, O.; Krugliachenko, O.; Petrovskiy, Yu.; Rudenko, I. (2018)

According to WHO report 53,5% of adults in Ukraine are overweight and 21,3% are obese. In addition, MOH of Ukraine reports STIs (Sexually transmitted infections) as a national problem of Ukrainian healthcare. The aim of ...
Covid-19 pandemy effect on educational process in simulation medical technologies with standardized patients application

Rogachevskyi, O. P.; Pervak, M. P.; Onyshchenko, V. I.; Yehorenko, O. S. (2022)

During the development of COVID-19 pandemicallover the world, many educational institutions have undergone changes in the educational process and modified their lessons as online classes. It is having a big influence ...
Daytime sleep-wakefulness cycle disturbances are effectively reversed with pitolisant in pentylenetetrazol-kindled rats

Yehorenko, O. S.; Pervak, M.; Latypov, K. A.; Prybolovets, K.; Shcheglov, I. A.; Godlevsky, L. S. (2023)

Chronic brain eptisation induces sleep-wakefulness (SW) disturbances. The work aimed to investigate SW cycle in pentylenetetrazole (PTZ)- kindled rats under combined treatment with the histamine H₃ inverse agonist ...
Effects of a Combination of Transcranial DC Cerebellar Stimulation and Pioglitazone Administration on Pentylenetetrazole-Induced Seizures in Kindled Rats

Godlevsky, L. S.; Poshyvak, O. B.; Pervak, M. P.; Latypov, K. A.; Prybolovets, K. O.; Yehorenko, O. S. (2021)

In rats with the kindling syndrome induced by i.p. injections of pentylenetetrazole (PTZ; 35 mg/kg daily, for three weeks), the averaged latency of seizures induced by a test injection of PTZ (35 mg/kg) was significantly ...
Effects of cerebellar transcranial direct current stimulation upon kindled seizures depends upon PPARγ modulation

Pervak, M.; Godlevsky, L. (2019)

The purpose of the investigation was to estimate the effectiveness of peroxisomal proliferator-activated γ-receptors (PPARγ) modulation upon the antiseizure effects of transcranial direct current stimulation (tDCS). In ...
Effects of silver nanoparticles on pentylenetetrazol-induced kindled seizures in rats

Pervak, M. P.; Первак, М. П.; Первак, М. П. (2019)

Silver nanoparticles are used for delivering neurotropic agents to brain, increasing the bioavailability of insoluble drugs as well as for brain tumours treatment. Their effects upon brain excitability, especially under ...
Emergency conditions as simulation medical scenarios for applicants of education

Pervak, M. P.; Onyshchenko, V. I.; Yehorenko, O. S.; Karakonstantyn, D. F. (2021)

Emergency conditions are very life-threatening situations and require fast actions and immediate intervention from medical stuff. For young doctors without extensive experience in the treatment of these important diseases, ...
Enhancement of the anticonvulsant effect of the h3 histamine receptor blocker thioperamid against the use of pioglitazone

Yehorenko, O. S.; Pervak, M. P.; Poshyvak, O. B.; Liashenko, A. V.; Godlevsky, L. S. (2022)

The purpose of the study was to study the dynamics of foci of epileptic activity, which were reproduced in the cerebral cortex of kindled rats using the sodium salt of benzylpenicillin, under the conditions of individual ...
Features of mastering practical skills by students during the Covid-19 pandemic using simulation training methods

Pervak, M.; Yehorenko, O. (2021)

Observed the mastery of practical skills, as competencies for compiling OSСE (Objective structured clinical examination), by 6th year students and interns of various specialties in Odessa national medical university ...
Functional links in the brain cortex of kindled rats evaluated at different stages of kindling seizures precipitation

Pervak, M. P.; Godlevsky, L. S. (2023)

The work investigated the relationships between brain structures established in different periods of pentylenetetrazol (PTZ)-induced kindled seizure precipitation. As structures for investigations, the cortical ones of ...
General surgery. Selected lectures : a manual for students of higher medical educational establishments of the IV level of accreditation using English

Vansovych, V. Ye.; Voloshenkova, N. D.; Davydov, D. M.; Dmytriyev, B. I.; Zhuravok, O. I.; Kadochnikov, V. S.; Mishchenko, V. V.; Savvov, V. I.; Stepanov, Yu. I.; Torbynsky, A. M.; Вансович, В. Є.; Волошенкова, Н. Д.; Давидов, Д. М.; Дмитрієв, Б. І.; Журавок, О. І.; Кадочніков, В. С.; Міщенко, В. В.; Саввов, В. І.; Степанов, Ю. І.; Торбинський, А. М. (OSMU, 2009)

The textbooks on general surgery course published the previous years have lost their actuality on some problems. The curriculum organization on the credit-module system basis according to the new syllabus requires new ...
Immunohistochemical neuroinflammatory markers in the hippocampus of PTZ-kindled rats under conditions of rapamycin and axitinib treatment

Poshyvak, O.; Pinyazhko, O.; Godlevsky, L.; Pervak, M.; Yehorenko, O.; Doganyigit, Z.; Okan, A.; Akyuz, E.; Hathal, N. A.; Liashenko, A. (2023)

The aim of the study is to determine the level of HIF-1α, TNF-α, and NF-kB in the hippocampus of kindled rats treated with rapamycin and axitinib. Materials and methods. Kindling was produced in 29 rats by administration ...
Intravesical hyperthermic chemotherapy with mitomycin C in patients with non-muscle-invasive bladder cancer, initial experience in a single center

Kostev, F. I.; Chystiakov, R. S.; Lysenko, V. V.; Stavnychyi, O. S.; Rosha, L. G. (2019)

The EUA 2018 guidelines recommend that patients with high-risk NMIBC receive either intravesical BCG or radical cystectomy. BCG therapy is difficult to tolerate by patients and some patients are not suitable for cystectomy. ...
Laparoscopic repair of hiatal hernias and nissen fundoplication: analysis of long-term results, new classification and future trends

Grubnik, V. V.; Malynovskyy, A. V.; Грубник, В. В.; Малиновский, А. В. (The Odessa National Medical University, 2012)

The choice of method of hiatal hernia repair is still controversial. Recurrences after repair of large and giant hiatal hernia reach 42%. Mesh repair may decrease failure rate but bears risk of oesophageal complications. ...
Magnetic resonance imaging with diffuse weighted imaging and computed tomography with intravenous contrast in staging of disseminated ovarian, stomach, colorectal cancer

Chetverikov, S; Zavoloka, S.; Onyshchenko, V.; Chetverikov, M.; Chetverikova-Ovchynnyk, V. (2019)

The aim of the research. Development and implementation of new methods for pre-operative staging of advanced ovarian, gastric and colorectal cancer to improve patient selection for cytoreductive surgery and increase its ...
Mastering of clinical skills by applicants of education during simulation medical scenarios directed to treatment of patients with seizure activity

Rogachevskiy, O. P.; Pervak, M. P.; Yehorenko, O. S.; Karakonstantyn, D. F. (2022)

Emergency medical conditions are life-threatening and need immediate intervention of professionals. Such cases are the most critical for the people's vital health care. It is crucial for emergency departments to create the ...

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