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Перегляд Кафедра загальної і клінічної фармакології та фармакогнозії за назвою

Перегляд Кафедра загальної і клінічної фармакології та фармакогнозії за назвою

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Association between effectiveness of tuberculosis treatment and cytochrome P-4502E1 polymorphism of the patients

Antonenko, P.; Butov, D.; Kresyun, V.; Butova, T. (2017)

Context: The risk of antituberculosis (TB) drug‑induced liver injury could be determined by patients’ genotype polymorphism of the xenobiotic‑metabolizing enzymes. To find the meaning of cytochrome P‑4502E1 (CYP2E1) ...
Biochemical Value Dynamics in Patients with Multidrug‑Resistant Tuberculosis/HIV with CD4+ Lymphocyte Cells below 50 Cells/μCL and its Variability in the Application of Adjuvant Immunoglobulin Therapy

Matsegora, N. A.; Kaprosh, A. V.; Antonenko, P. B. (2019)

Treatment of the patients with multidrug‑resistant tuberculosis (MDR‑TB)/HIV coinfection in a state of severely suppressed immune system remains under effcient. Aims: The aim of this study was to assess the effectiveness ...
Can we assess the CYP3A4*1G polymorphism as a predictor of the hepatotoxicity during antituberculosis therapy?

Poludenko, H. O.; Antonenko, P. V.; Antonenko, K. O. (2021)

The aim of this research was to find the meaning of CYP3A4*1G polymorphism in TB patients for the toxicity development during inpatient TB treatment. Figure Thus according to CYP3A4*1G genotype after completion of ...
Condition of periodontal tissues on the background of Helicobacter invasion: the concept of pathogenesis

Bohatu, S.; Rozhkovsyi, Ya.; Lyubchenko, O. (2023)

he aim: To analyze the state of periodontal tissues against the background of Helicobacter pylori invasion in dynamics and to propose a possible mechanism of development of in%ammatory periodontal diseases in patients ...
Content of biologically active compounds in fruits of capsicum annuum L

Boyko, Yu.; Boyko, I. (2023)

The study of the chemical composition of natural raw materials allows not only to obtain data on the peculiarities of its structure and organization, but also to find new chemical compounds with useful qualities. The search ...
Current view on the problem of treating fibrocystic breast disease in terms of herbal medicine

Sokolik, O. P.; Prozorova, G. O. (2022)

Introduction: Fibrocystic breast disease, commonly called fibrocystic breasts or fibrocystic change, is a benign (noncancerous) condition, which is the most common pathology in women of reproductive age. Treatment of ...
Detection of Mycobacterium tuberculosis rifampicin resistance by polymerase chain reaction

Antonenko, P.; Kresyun, V.; Antonenko, K.; Антоненко, П. Б.; Кресюн, В. Й.; Антоненко, К. О. (2014)

The goal of this research was detection of the rifampicin-resistance level of M. tuberculosis infection in the Odessa region of Southwest Ukraine, investigation of the level of mutation at codons 516, 526, 531 in the rpoB ...
Dose-dependent effect of hexadecyl ester of ibuprofen on the model of formalin-induced inflammation

Prystupa, B. V.; Bogatu, S. I.; Kresyun, V. Y.; Boiko, I. A.; Unhurian, L. M.; Приступа, Б. В.; Богату, С. І.; Кресюн, В. Й.; Бойко, І. А.; Унгурян, Л. М. (2024)

Inflammation is a protective reaction of the organism to the damaging agent. Ibuprofen has anti-inflammatory, antipyretic, and anti-edema effect. But ibuprofen has also side effects. The main goal was to estimate the ...
The effect of a new combined feed on some physiological parameters of laboratory rats

Boiko, Yu.; Boiko, I. (2024)

For normal growth, development and vital activity, laboratory animals must receive a complete feed ration. A new feeding ration for rats was proposed, which is based on the use of combined feed PC 120-1. A comparison was ...
Effect of Low-Frequency Ultrasound on Transdermal Delivery of Ibuprofen Esters

Kravchenko, I.; Prystupa, B. (2021)

Ultrasound therapy is included in the basic program of physiotherapeutic treatment of inflammatory joint diseases. Recently, low-frequency ultrasonic vibrations are often used in physiotherapy practice. The biological ...
The effect of mucosal-adhesive phytogels “Kvertulin” and “Lekvin” on the state of the oral cavity in patients with helicobacter pylori-associated pathology of gastroduodenal area by the data of dental indices

Bogatu, S. І. (2019)

The article presents information about the state of the oral cavity according to dental indices in patients with chronic gastritis and gastroduodenitis, associated with Helicobacter pylori, before and after eradication ...
The effectiveness of treatment of pulmonary tuberculosis depending on CYP3A4 genotype

Poludenko, H. A.; Antonenko, P. B.; Rozhkovskyi, Y. V.; Antonenko, K. A.; Lobashova, K. G. (2022)

Among the factors that can influence the course and effectiveness of the treatment of pulmonary tuberculosis (TB) the genetic characteristics of patients play an important role. It is established that cytochrome (CYP) 3A4/5 ...
Efficacy of systemic administration of riboflavin on a rabbit model of corneal alkali burn

Żuk, M.; Lobashova, E.; Żuk, O.; Wierzba, S. (2020)

Changes in the barrier mechanisms in the eye should determine the rational route for the administration and dosage of each drug in the treatment of traumatic injuries and other pathologies. The aim of this study was to ...
The Element Composition Study of Thick Extract from Tribulus terrestris L. Herb

Burda, N. Ye.; Dababneh, M. F.; Klivniak, B. M.; Zhuravel, I. A.; Rozhkovsky, Ya. V. (2016)

The element composition of thick extract from caltrop herb was studied by the atom-emission spectroscopic method. The content of 19 elements was determined. Potassium, sodium and calcium dominated among the mineral elements. ...
The experimental - computer technology for pathological process simulation

Zaporozhan, V. N.; Karpovsky, Ye. Ya.; Bazhora, Yu. I.; Kresyun, V. I.; Servetsky, K. L.; Andronov, D. Yu.; Procuda, O. F. (1996)

The technology of pathological process and its treatment simulation in conditions of sharing of results of experimental supervision and computer simulation is considered.
Express identification of Mycobacterium tuberculosis in different biologycal samples

Nickolaevsky, V.; Asmolov, A.; Bazhora, Yu.; Vladimirsky, M.; Kresyun, V.; Filyuk, V. (2001)

Tuberculosis morbidity is increasing constantly in Ukraine and in Odessa region as well. In 2000 children morbidity have run up to 6,5 by 100, 000 children, adolescents to 33,4; adults – to 41,9 by 100,000 citizens. The ...
Features of lipid metabolism in membranes of rat cells at experimental traumatic brain injury on the background of chronic alcohol intoxication

Kresyun, V.; Godovan, V.; Sokolik, E.; Kresyun, N. (2022)

Alcohol intoxication is often the cause of traumatic brain injury. The purpose of the work was to study the features of lipid metabolism in erythrocytes and mitochondria of the cerebral cortex cell membranes of rats in ...
Features of protein metabolism during inflammation under terms of transdermal injection of ginger extract

Eberle, L. V.; Kobernik, O. O.; Kravchenko, I. A. (2018)

In recent years, interest in plant medicines, which have a mild physiological effect, minimal toxicity, non-addictive, absence of immunosuppression, the possibility of prolonged use, has increased. One of the medicinal ...
Features of vascular-thrombocitic and plasmacoagulative links of hemostais in the women with antenatal death of fetus

Nikogosian, L. R.; Никогосян, Л. Р. (2013)

Indexes of vascular- trombocitic and plasma-coagulative links of hemostasis have certain features in pregnant with antenatal death of fetus. They are characterized by the signs of hypercoagulation in the Іst and hypocoagulation ...
Field training in pharmaceutical botany: diary

Rozhkovsky, Ya. V.; Prystupa, B. V.; Gerasimyuk, N. V.; Boyko, I. A.; Chernogoryuk, V. V.; Bogatu, S. I. (2022)

The publication is intended for full-time and part-time students in the specialty “Pharmacy” and is a reporting document on field training practice, provides familiarity with general provisions, thematic plans, ...

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Перегляд Кафедра загальної і клінічної фармакології та фармакогнозії за назвою

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