Нами разработан реминерализирующий гель для полости рта «Слюрем» с эффектом искусственной слюны для лиц с гипосаливацией. В состав геля включены препараты кальция, фосфора и фтора. Кариеспрофилактическую эффективность геля изучали на двух моделях снижения саливации: первая обусловлена токсическим поражением слюнных желез метилметакрилатом, вторая — атропиновая модель. Исследования показали, что гель для полости рта «Слюрем» уменьшает распространенность
и интенсивность кариеса.
Researches were conducted on experimental animals — white rats. We developed remineralization gel for the oral cavity “Slurem” with the effect of artificial saliva for persons with sialoschesis. The composition of gel included preparations of calcium, phosphorus and fluorine. Efficiency of gel was studied on 2 models of sialosis decrease: the first one is caused by toxic defeat of salivary glands by methylmethacrylate, the second one — atropine model.
The results and discussion. The results of research showed that prevalence and intensity of caries at treatment of mucous membraine of the oral cavity for animals increased a monomer almost by 20%, and at treatment an atropine — more than by 28% as compared to intact animals. Application of gel considerably brought down prevalence and intensity of caries on both models of salivary glands (treatment of mucous membraine of the oral cavity by monomer by 39.7% and by atropine — by 43.7%).
