N 6 (197) 2025. P. 61–64

CLINICAL AND FUNCTIONAL RATIONALE FOR THE USE OF WHITENING AND DESENSITIZING TOOTHPASTES IN MIDDLE-AGED PATIENTS

State Establishment “The Institute of Stomatology and Maxillo-Facial Surgery National Academy of Medical Sciences of Ukraine”, Odesa, Ukraine

DOI 10.32782/2226-2008-2025-6-9

Aesthetic and functional enamel parameters, such as colour stability and dentinal sensitivity, are key indicators of oral health and patient quality of life. Modern dentifrices often combine whitening, remineralizing, and desensitizing components, yet long-term comparative evaluation of their optical and electrofunctional effects remains limited. Aim – to assess changes in colour (saturation, brightness, whiteness, and yellowness indices) and electroodontometric parameters of permanent teeth in adults using toothpaste formulations with different ratios of whitening, remineralizing and desensitizing agents over short- and long-term periods.

Materials and methods. The study population comprised adults allocated into four groups, with each group assigned a toothpaste formulation differing in its predominant whitening, remineralizing or desensitizing effect. Optical enamel characteristics were measured by spectrocolourimetry, and pulp excitability was determined using electroodontometry at baseline and after 1, 3 and 6 months of product use.

Results. Toothpastes with predominant whitening–remineralizing action produced a significant reduction in colour saturation and yellowness with a stable increase in brightness and whiteness from the first month of use, maintaining the effect throughout the observation period. In contrast, formulations with a dominant desensitizing component provided moderate optical improvement but demonstrated a pronounced increase in pulp excitability, indicating activation of reparative tissue responses.

Conclusions. Dentifrices with varying combinations of whitening, remineralizing and desensitizing agents exert differential effects on enamel and pulpal tissues, supporting an individualized selection strategy depending on the intended clinical outcome – aesthetic enhancement or functional recovery.

Key words: middle-aged adults, toothpaste, dentin hypersensitivity, spectrocolourimetry, electroodontometry.

REFERENCES

  1. Freitas M, de Carvalho M, Liporoni P, et al. Effectiveness and Adverse Effects of Over-the-Counter Whitening Products on Dental Tissues. Frontiers in Dental Medicine. 2021;2:687507. doi: 10.3389/fdmed.2021.687507.
  2. Khan M, Nisa W. Sound Induced Dental Sensitivity: Sound Causes Dental Sensitivity. Pakistan Journal of Health Sciences. 2024;5(11):313–315. doi: 10.54393/pjhs.v5i11.2154.
  3. Golonka K, Gulla B, Kościelniak D, et al. Sensory processing sensitivity in adult dental patients and its relation to perceived stress, cortisol, and serotonin secretion. Scientific Reports. 2025;15(1):7328. doi: 10.1038/s41598-025-90263-1.
  4. Yunakova NM. Alhorytm efektyvnoi diiahostyky chutlyvosti zubiv: rekomendatsii za rezultatamy memorandumu ekspertiv krain Tsentralnoi ta Skhidnoi Yevropy, kviten 2021 r. [Algorithm for effective diagnostics of tooth sensitivity: recommendations based on the results of the memorandum of experts from Central and Eastern Europe. April 2021]. Modern Dentistry. 2021;4:12–14. (In Ukrainian). doi: 10.33295/1992-576X-2021-4-12.
  5. Vano M, Derchi G, Barone A, Pinna R, Usai P, Covani U. Reducing dentine hypersensitivity with nano-hydroxyapatite tooth-paste: a double-blind randomized controlled trial. Clin Oral Investig. 2018;1:313–320. doi: 10.1007/s00784-017-2113-3.
  6. Barbosa LM, Carneiro TS, Favoreto MW, et al. Effect of whitening toothpastes with different hydrogen peroxide concentrations: Penetration into the pulp chamber and color change. Journal of Dentistry. 2024;144:104951. doi: 10.1016/ j.jdent.2024.104951.
  7. Skrypnikova TP, Kulay OO, Khmil TA, Tymoshenko YV, Khawalkina LM. Fluoride-containing agents in the treatment of dentin hypersensitivity. Ukrainian Dental Almanac. 2025;1:10–17. (In Ukrainian). doi: 10.31718/2409-0255.1.2025.02.
  8. Gurzhiy OV, Skrypnikova TP, Kulay OO, et al. Modern principles of non-invasive treatment of dentin hypersensitivity. Ukrainian Dental Almanac. 2024;3:19–25. (In Ukrainian). doi: 10.31718/2409-0255.3.2024.02.
  9. Dionysopoulos D, Papageorgiou S, Papadopoulos C, Davidopoulou S, Konstantinidis A, Tolidis K. Effect of Whitening Toothpastes with Different Active Agents on the Abrasive Wear of Dentin Following Tooth Brushing Simulation. Journal of Functional Biomaterials. 2023;14:268. doi: 10.3390/jfb14050268.
  10. Suriyasangpetch S, Sivavong P, Niyatiwatchanchai B, et al. Effect of Whitening Toothpaste on Surface Roughness and Colour Alteration of Artificially Extrinsic Stained Human Enamel: In Vitro Study. Dentistry Journal. 2022;10(10):191. doi: 10.3390/dj10100191.
  11. Patent No. 18966 Ukraine, MPK A61B 1/24 (2006.01), G01N 21/25 (2006.01). Optical express method for in vivo monitoring of changes in the degree of mineralization of hard dental tissues. OV Dienha, EM Dienha; No. u 2006 07222; Appl. 29.06.2006; Publ. 15.11.2006; Bull. No. 11/2006.9 (in Ukrainian).
  12. Holovanova IA, Byelikova IV, Lyakhova NO. Osnovy medychnoyi statystyky: navchalniy posibnyk dlya aspirantiv ta klinichnykh ordynatoriv [Fundamentals of medical statistics: a textbook for postgraduate students and clinical residents]. Poltava, 2017. 113 р. (In Ukrainian). Available from: https://repository.pdmu.edu.ua/items/3d7e3785-6ead-44d3-9023-e4aae2b28c0c.