N 1 (186) 2024 р. P. 18–23

RETROSPECTIVE ANALYSIS OF DIAGNOSTIC IMAGES OF LYMPHOPROLIFERATIVE DISORDERS

V. M. Sokolov, G. M. Rozhkovska, V. M. Tsvigovsky,
T. K. Dorofeyeva, O. A. Korsun, O. O. Dolgushin, O. M. Dius, O. D. Slyusarenko, A. S. Arbatska

Odesa National Medical University, Odesa, Ukraine

DOI 10.32782/2226-2008-2024-1-3

The analysis is aimed at comparing the results of independent studies of the radio tomographic picture of lymphoproliferative diseases with different localization of the pathological process and the experience of leading international organizations studying the diagnostic criteria of various types of lymphomas, such as the National Comprehensive Cancer Network (NCCN), the European Society for Medical Oncology (ESMO), EORTS, and ASCO, which allow diagnosing lymphoproliferative diseases and planning therapy based on the interpretation of PET/ CT and contrast-enhanced CT data (assessment of treatment effectiveness on a 5-point Deauville scale). The analysis is based on the results of original studies of 156 patients with lymphomas of various localization, including lymph nodes, gastrointestinal tract, spleen, pancreas, kidneys, adrenal glands, etc. Lymphomas are malignant neoplasms arising from mature lymphocytes. The incidence of Hodgkin’s lymphoma in Ukraine is approximately 2.4 cases per 100,000 population. Lymphomas are classified according to the 2022 WHO classification of tumors of hematopoietic and lymphoid tissues based on the cells of origin. At the same time, radio tomographic examination reveals characteristic features of lymphoproliferative diseases: thickening of organ walls, wall deformation, presence of lymphadenopathy, and others. The specifics of organ involvement are highlighted, emphasizing the importance of PET/CT and contrast-enhanced CT as diagnostic and staging tools, as well as for monitoring the course and effectiveness of treatment of lymphoproliferative diseases.

Key words: lymphoproliferative diseases, computer tomography, lymph nodes, gastrointestinal tract, spleen.

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