The research of the influence of various levels of the hyperhomocysteinemia at the mutation of methylentetrahydrofolatereductase (МТНFR) on the system of the hemostasis was carried out. 170 patients were examined with various obstetrical pathology in the anamnesis.
The offered pathogenetic algorithm of treatment of thrombophilic condition in patients with fraxiparin, a folic acid, vitamin В6, В12, antioxidants has given a positive effect. It will enable to exclude the further perinatal losses.