With the usage of computer simulation methods biopharmaceutical and physicochemical parameters of biphenyl molecules were compared with those of losartan, valsartan and flurbinofen. The results indicate rapid transit of these drugs along the gastrointestinal tract, so the question is the mechanism of absorption. For further study we used 4-3H-diphenyl as a marker. It is shown that losartan, valsartan and flurbinofen with sufficient speed comes from the stomach to the alternative “window of absorption” — the small intestine — and absorb by passive diffusion through the mucous membrane.
