Oxidant and antioxidant status in smoking mothers and their newborns (Literature review)

Abstract

Environmental tobacco smoking is known to be associated with adverse pregnancy outcomes. Maternal cigarette smoking accompanied with fetal and neonatal growth restriction causes abnormalities in organ development in the postnatal life. Smoking cessation influences the risk of infant death. Placenta tissue may be a major source of lipid peroxidation (LPO) products in pregnancy. Increased lipid peroxidation and reduced antioxidant activity may contribute to the development of complications in pregnancy. Associations between both maternal smoking and infant irritability and later behavioral disregulation have important implications for early identification and intervention with at-risk offspring.