Цель исследования — провести характеристику эпигенетических факторов у женщин репродуктивного возраста во взаимосвязи с лейомиомой матки с точки зрения выбора патогенетически обусловленной профилактики. Обследовано 300 женщин репродуктивного возраста. К основным эпигенетическим факторам риска возникновения и прогрессирования лейомиомы матки следует отнести влияние места проживания; возраст высокой репродуктивной активности; состояние хрониостресса, который тесно связан с социальным статусом; неконтролируемый в большинстве случаев прием лекарственных препаратов, наличие вредных привычек; несбалансированное, нерегулярное, некачественное питание; недостаточную двигательную активность.
Determination of epigenetic risk factors and growth of uterine leiomyoma is of immense practical
importance in terms of pathogenesis due to prevention.
Research objective was to make the characteristic epigenetic factors at women of reproductive
age to interrelations with leiomyoma of uterus from the point of view of a choice for pathogenetically
caused preventive maintenance. There were examined 300 women of reproductive age. The epigenetic
risk factors of uterine leiomyoma are following: residence, age of high reproductive activity which
is closely connected with the state of hormonal function, the state of chroniostress associated with the
social status; uncontrollable intake of drugs and bad habits; unbalanced, irregular, poor-quality food;
insufficient motor activity. From the point of view of a choice for pathogenetically caused preventive
management of occurrence and progressing uterine leiomyoma, especially of proliferative type, it is
necessary to consider the epigenetice factors role in order to decrease their damaging action during
prenatal development, puberty, reproductive age.
