N 2 (183) 2023. P. 88–93

OUTCOMES OF USING XENOGENEIC MATERIALS FOR GINGIVAL RECESSION TREATMENT: ANALYSIS OF SYSTEMATIC REVIEWS AND META-ANALYTICAL STUDIES’ DATA

Uzhhorod National University, Uzhhorod, Ukraine

DOI 10.32782/2226-2008-2023-2-16

There are significant number of systematic reviews and meta-analyses dedicated to the evaluation of the effectiveness of various graft types and surgical techniques used for the treatment of gingival recession. However, only few of them are dedicated to the analysis of using specifically xenogenic materials for the gingival recession treatment.

The aim of the study. To analyze the data of systematic reviews and meta-analytical studies regarding clinical effectiveness of xenogeneic materials use for gingival recession treatment.

Materials and methods. The initial search for systematic reviews and meta-analytical studies was carried out within the PubMed (NCBI) (https://www.ncbi.nlm.nih.gov/pubmed/) database by the keywords “recession” and “xenogeneic” while also using the filters “Systematic review” and “Meta-analysis”. Additional search for relevant publications was provided via Google Scholar (https://scholar.google.com/) engine while using similar keywords and advanced search capabilities.

Results. Overall 12 systematic reviews and meta-analytical studies were analyzed. In most of the systematic reviews and meta-analyzes data regarding clinical benefits of using xenogeneic materials in combination with surgical techniques for the gingival recession treatment was characterized by the high degree of heterogeneity. The additional use of xenogeneic collagen matrix in combination with coronary-advanced flap characterized with the better clinical outcomes for recession treatment compare to the results obtained with coronally-advanced flap separately, while the objective clinical benefits of such approach vary.

Conclusions. Despite the registered data heterogeneity extracted from systematic reviews, it was established that xenogeneic collagen matrix may be used as perspective material in combination with surgical techniques for gingival recession treatment, and such approach may be interpreted as an alternative in the condition of limited possibilities for using connective tissue graft, acellular dermal matrix and enamel matrix derivatives with the analogical objective.

Key words: gingival recession, xenogeneic collagen matrix, systematic reviews.

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