PECULIARITIES OF FUNCTIONAL CONDITION OF PRO-OXIDANT AND ANTIOXIDANT SYSTEMS IN HEPATIC TISSUE OF GUINEA PIGS IN THE FORMATION OF EXPERIMENTAL BRONCHIAL ASTHMA AND THEIR CORRECTION WITH THIOTRIAZOLINE

Disturbance of functional condition of pro-oxidant and antioxidant systems, accompanied by increase in the content of diene conjugates and malonic dialdehyde, as well as decrease in activity of superoxide dismutase and catalase in hepatic tissue in experimental bronchial asthma has been shown in the research.

Administration of antioxidant thiotriazoline has a corrective influence on the processes of peroxide lipid oxidation and condition of antioxidant system enzymes.