In experimental traumatic brain injury condition of hypothalamic-adrenal and hypothalamic-thyroid systems according to their dynamic blood levels was investigated. Total regularities of traumatic disease duration were oppression of functional activity of hypothalamic-thyroid system, which had good relation with trauma severity and which is found to the end of the first day; decrease of somatotropin secretion; activation of central and peripheral links of hypothalamic-adrenal system with next exhaustion of adrenal functional activity in unfavorable duration. Significant prognosis factors of traumatic disease duration severity are the degree of somatotropin, triiodthyronin, corticosteron blood levels decreasing.
