PECULIARITIES OF ACTIVITY OF NA+-, К+-ATPASE IN ERYTHROCYTES OF POSTERITY RECEIVED FROM TOXICALLY AFFECTED BEFORE CONJUGATION MALE AND FEMALE RATS

As a result of researches it was settled that in ontogenesis of posterity, received from intact male and female rats starting from the second week and till 3-month age the activity of Na+-, К+– ATPase in erythrocytes gradually increased, which was stipulated by the necessity of developing and sex maturation of these animals. In posterity of rats, received from toxically affected male and female rats, at all the stages of ontogenesis the decreasing of activity of Na+-, К+– ATPase concerning the indices of same-age control was observed. The revealed changes confirm that toxic affecting by CCl4 of males and females before conjugation caused decreasing of activity of Na+-, К+– ATPase in following generations.