There are determined prognostic criteria of effective HR control in patients with permanent AF treated by amiodarone and with metoprolol or сarvedilol combination with initial clinical signs and HRV indices with the use of equations construction of discriminative functions. Prognostically meaningful parameters for determination of efficiency therapy in permanent AF in group of patients which got monotherapy with amiodaronе were HR, the LA size, level of DAP and TP spectrum HRV; in the group treated by combination of amiodarone with metoprolol were HR, FC HF the LA size and AF remoteness and in the group treated by combination of amiodaronе with carvedilol were HR, remoteness of AF, QLI and TP spectrum HRV.
