Sleep disorders are one of the seroius problems for present medical science, that’s why the studying of new pharmaceutics (for example, 1.4-benzdiazepine derivatives) for therapy is of great importance. The aim of this work was determination of cinazepam methabolites and its elimination after intravenous administration in mice.
It was found, that after intravenous administration with urine and feaces 85% of the dose is excreted during 96 hours, and only 4% of cinazepam unchanged.