MODULATION OF TRANSPORTING ACTIVITY OF THE SMALL INTESTINE OF RATS BY PREPARATION «LEGALONUM» AND EXTRACT OF GARDEN-STUFFS OF SPOTTED RASTOROPSHA

Comparison of the effects of patent pharmacological preparation became the purpose of work «Legalonum» and biologically active addition from the garden-stuffs of spotted rastoropsha Silybum marianum (L.) Gaertner, containing sylymaryn as a basic operating component, on the transport of glycine and glucose from their 10 mmol/l solutions into the accumulate preparations from the rats’ small intestine mucous.

It was shown that legalon and dried up hydroalcoholic extract of garden-stuffs of spotted rastoropsha for certain braked both the transport of glycine in preparations from the rats’ small intestine mucous (by 47 and 46 % accordingly) and transport of glucose (by 28 and 33 % accordingly).