The aim of researches is learning nephroprotective qualities of glutargyn based on a long-term iphosphamide administration to white rats. Administration of iphosphamide to white rats causes significant changes in the kidneys function: reduction of speed of glomerular filtration, the concentrating index of creatinine, increasing of proteinuria and osmotically active substances and protein excretion.
At the same time, the combination of glutargyn and iphosphamide administration to rats has a nephroprotective effect, which promotes normalization of above-mentioned indices.