ANTIVIRAL ACTION OF THE BIS- QUARTERNARY AMMONIUM BASES AGAINST THE AVIAN INFLUENZA VIRUSES

In vitro antiviral activity of E-aminocaproic acid and unithiolum were studied on the model of avian influenza virus strains H5N3 and H7N3 replication in the tissue culture of 11–14-days age chicken embryos’ choryoallantoic membranes (CAM). It was determined that unithiolum in a dose of 10 mg/ml and E-aminocaproic acid in a dose of 15 mg/ml have inhibited the reproduction of avian influenza viruses strains H5N3 and H7N3. So, usage of these medicines is a perspective approach for protection and therapy of avian influenza viral infections.