THE PATHOGENETICAL ROLE OF CYTOKINES OF SPECIFIC INFLAMMATION PECULIARITIES IN PATIENTS SUFFERING FROM DESTRUCTIVE PULMONARY TUBERCULOSIS

The essential difference of the contents of proinflammatory and antiinflammatory cytokines depending on the phase of the inflammation was established by immune-enzyme analysis of expired air kriocondensate in patients with dectructive pulmonary tuberculosis. On the background of interferon-γ hyperрroduction (more than twice) in the excudative phase of the specific inflammation interleukin-1β and tumor necrosis faсtor-a cytokines are synthetised mainly whereas in a productive phase — transforming growth factor-β1