The essential difference of the contents of proinflammatory and antiinflammatory cytokines depending on the phase of the inflammation was established by immune-enzyme analysis of expired air kriocondensate in patients with dectructive pulmonary tuberculosis. On the background of interferon-γ hyperрroduction (more than twice) in the excudative phase of the specific inflammation interleukin-1β and tumor necrosis faсtor-a cytokines are synthetised mainly whereas in a productive phase — transforming growth factor-β1