SUBSTANTIATION OF ANGIOPROTECTOR ISODIBUTUM APPLICATION EFFICIENCY FOR TREATMENT OF GENERALIZED PARODONTITIS IN RATS UNDER EXPERIMENTAL DIABETES

It is proved, that isodibutum application in white rats under experimental diabetes promotes reduction of gingival capillaries permeability. It indicates a stabilizing action of the preparation on a resistant condition of parodontium tissues capillaries. An optimal concentration for local application is 5 % water isodibutum suspension.