PARALOGS AND ORDER OF DUPLICATION OF HUMAN ALCOHOL DEHYDROGENASE ENCODING GENES

By phylogenetic analysis of nucleotide sequences the order of duplication of homologues of human alcohol dehydrogenase genes ADH1A, ADH1B, ADH1C, ADH4, ADH5, ADH6 and ADH7 was determined by Maximum Likelihood method. A dendrogram was constructed according to result of conducted phylogenetic analysis. Evaluation of the evolutionary divergence between sequences of the studied genes was made.