THE STUDY OF CLINICAL-GENEALOGICAL FACTORS OF WOMEN, WHO GAVE BIRTH TO CHILDREN WITH CONGENITAL HEART DISEASE

The purpose — to study the features of clinical and genealogical history in women who gave birth to children with congenital heart disease (CHD).

Materials and methods. The collection for the analysis of clinical and epidemiological and medical-statistical data of primary medical documentation was carried out: and 170 cards of pregnant women who gave birth to children with CHD for 5 years (2011–2015 years) and 170 cards of women who gave birth to healthy children.

Results of the research and discussion. The study of the influence of harmful factors on the course of pregnancy found that women in the main group reliably suffered from viral respiratory disease during pregnancy. Most patients in the main group have been diagnosed somatic diseases: significantly more than the control group, women with CHD of fetus were noted cardiovascular diseases, urinary tract, and also a combination with endocrine pathology and chronic infectious diseases. The main complications of reproductive history in females with CHD of fetuses were involuntary miscarriages and still birth pregnancies. Also, in women who gave birth to children with congenital heart disease, 8 (4.7%) cases of fetal bovine disease were documented. In the control group, significantly more patients did not notice the characteristics of reproductive history, and the number of unauthorized miscarriages, still birth pregnancies, and the birth of children with birth defects was significantly lower. In women with CHD of fetuses, complications of gynecological history, most often infertility and myoma of the uterus, have been observed.

Conclusions. As a result one can assert that the risk factors for the occurrence of congenital heart defects in children may be the age of the mother (over 35 years of age), hereditary factor, the risks associated with chronic somatic disease, namely the cardiovascular system, the urinary system, and their combination with endocrine pathology, reproductive loss in history (involuntary miscarriage, still birth pregnancy, children with birth defects), complications of gynecological history, most often infertility and myoma of the uterus.