The aim of the study was to study the diastolic function of the left ventricle and the effect of hypoglycemic drugs of the group inhibitors SGLT-2 on the course of heart failure in patients with type 2 diabetes mellitus.
Materials and methods. In the course of the study, 20 patients with type 2 diabetes mellitus were examined. Doppler echocardiography was performed to evaluate the function of the left ventricle. To study the function of the endothelium, endothelium-dependent relaxation was determined using the Celermajer-Sorensen’s test and the level of endothelium-1 in serum. To assess heart failure, the level of NT-proBNP was performed before and after the addition of the iSGLT2 (dapagliflozin) group to the previously prescribed hypoglycemic therapy.
Results. During the follow-up period, a significant decreasing of NT-proBNP level was obtained after dapagliflozin preprescribtion.