Introduction. The condition of the vaginal biocenosis affects the general condition of the patient’s body, the course of the underlying disease and the concomitant pathology. Treatment of vaginal infections is based on the stage: empirical therapy; etiotropic antibacterial therapy; normalization of microflora and optimization of the state of the vaginal ecosystem; support of vital functions of lactobacilli, normalization of the function of the vaginal epithelium.
The aim of the study was to evaluate the effectiveness of the proposed algorithm for correcting the vaginal biocenosis of patients with uterine myoma.
Materials and methods of research. 216 patients with uterine myoma were examined. The effectiveness of traditional and proposed therapy in patients with uterine myoma was determined depending on the state of the vaginal biocenosis and by clinical signs, in comparison with the initial data and with each other.
Results of the study and their discussion. After the proposed therapy, the incidence of dysbiosis decreased in 2.7 times, vaginitis — in 4. 4 times, exocervicitis with cervical erosion — in 1.4 times, secondary posthemorrhagic anemia, hyperspolymenorrhea — in 1.7 times, respectively (p>0.05) — the difference is not reliable. The incidence of discomfort decreased by 2.2 times, pelvic pain, gravity in the lower abdomen, frequent urination — in 1.6 times, respectively, radiculcal syndrome — in 1.9 times, clinically significant (> 3 lg per 105 cells) human papilloma virus — in 2.4 times (p<0.05). Thus, the proposed therapy was better by the results of treatment in 2.2 times, or by 12.5 % in relation to traditional treatment.
Conclusions. The scientific novelty of the proposed algorithm consists in the simultaneous correction of the local and general biocenosis of the organism, in the preventive application of probiotics of local and general action, in the appointment before and after the surgical intervention of etiotropic therapy.