POSSIBILITY OF USAGE OF A COMPLEX OF IMMUNE HYSTOCHEMICAL MARKERS AT THE STAGE OF PRECLINICAL DIAGNOSIS OF EXTERNAL GENITAL ENDOMETRIOSIS IN INFERTILE WOMEN: PRELIMINARY DATA

The purpose of the study was to study the expression of estradiol and progesterone receptors, Ki-67 proliferation marker expression, MMP-9 cellular invasion and Bcl-2 apoptosis inhibitor in eutopic and heterotopic endometrial specimens in women of reproductive age with external genital endometriosis.

Materials and methods. 30 samples of eutopic and 30 samples of heterotopic endometrium in women of reproductive age with infertility and laparoscopically confirmed endometriosis were studied.

Results. The morphotype of the eutopic endometrium is characteristic for the external genital endometriosis.

Conclusions. The complex of immunohistochemical markers can be proposed as a minimally invasive manipulation for verifying the initial stages of endometriosis in women with infertility.