There were analyzed 198 patients (203 eyes) with severe stages of posterior form of proliferative vitreoretinopathy. In all cases pneumohydraulic melting of the retina and long vitreous tamponade of 20 % concentration of perfluoropropane (С3F8) were used. On 72 eyes (35.5 %) there were inferior retinal breaks. In 3 months of the follow up the retina was attached in 90.1 % cases (183 eyes), total retinal reattachment was in 59.6 % (121 eyes), reattachment of the central zone in 30.5 % (62 eyes). Visual acuity significantly increased χ2McNemar= 82.17; р=0.0000. The described method of vitreous surgery is effective and can be used for treatment of the patients with such a pathology.