FATTY-ACID SPECTRUM OF SERUM LIPIDS IN PATIENTS SUFFERING FROM DISSEMINATED TUBERCULOSIS

The study was aimed at studying and evaluating fatty-acid composition of serum lipids in patients suffering from disseminated pulmonary tuberculosis, by the biochemical method using a gas-liquid chromatograph. Essential changes were revealed in fatty-acid spectrum of serum lipids in patients suffering from disseminated pulmonary tuberculosis. They consisted in significant reduction in saturated fatty acid contents against a background of an elevation in total unsaturated fatty acid contents as well as total polyunsaturated fatty acid contents as a result of augmented activation of the lipid peroxidation processes.

The amount of arachidonic (C20:4) fatty acid grows up 3.0 times, and linoleic (C18:2) fatty acid 1.3 times as compared with the control group.