Endothelium-dependant vasodilatation, the concentrations of stable metabolites of NO and NO-synthase activity in plasma and in erythrocytes, and specific antivirus, antibacterial antibodies were studied in 118 young men of 16–40 years old with arterial hypertension. Presence of chronic infection with Chlamydia pneumoniae, Cytomegalovirus, Herpes simplex virus and Epstein — Barr virus were revealed in normotensive and hypertensive patients and with more prevalence in hypertensive men. Endothelium dysfunction is accompanied with increased deposition of stable metabolites of NO in erythrocytes and decreased NO-synthase activity in young men with intracellular infections which leads to increase in arterial blood pressure.
