In 1995 WHO registered tuberculosis epidemic in Ukrainе. Since then tuberculosis morbidity rate increase and it is 84.1 cases per 100,000 of population. Accoding to initiative of WHO control strategy on tuberculosis was made (DOTS). In Ukrainе DOTS strategy is adapted to national system of public health. The national programme of the control over tuberculosis in Ukrainе is elaborated on the base of DOTS strategy. The main tasks of the National programme have been presented in the article.