Treatment results of acute appendicitis were analyzed on two patient groups (the main and the one of comparison). In the main patient group we applied the lymphotropic method of drug injection. In the patient group of comparison the standard antibacterial empirical therapy was used. We collected result data of the indicators for CD3, CD4, CD8 and large granular lymphocytes on admission of the patient before appendectomy and on the 5th post-operative day. We observed that the quantity of CD3, CD4 and large granular lymphocytes was increased coming up to the control level after the lymphotropic injection of the antibiotics, meanwhile the quantity of CD8 was decreased. These findings confirmed dedicated influence of the lymphotropic therapy on the immune system. In the patient group of comparison the mantioned indicators were similar but not significant. In parallel to the immune response, we screened ultrasound measurements of the spleen and immune reactivity was corrected better in the patients with the regional lymphotropic approach. The presented method of the antibiotic therapy improves the treatment results and shortens the in-patient period.
