THE FEATURES OF NON-SPECIFIC IMMUNITY IN PREMATURE INFANTS

The purpose of research — is to study of the main factors of non-specific premature baby’s immune system.

Material and methods. As non-specific protection factors were chosen to study the C3 component of complement and C4-2, phagocytic index, the number of macrophages and NK-cells. The first group consisted of 62 children, born prematurely in the gestational age 34–36 weeks without perinatal pathological conditions. The control group was represented by 15 healthy newborns born at term 38–40 weeks of gestation.

Results. It has been shown that children born prematurely marked decrease in all indicators of nonspecific immunity. Among the non-specific humoral immunity is most pronounced decrease in the level of complement component C3. According to the results of studies of cellular immunity are most pronounced differences in the level of macrophages.