The study covers development and introduction of the method of laser-correlation spectroscopy (LCS) into dentistry, in particular, in orthopedic dentistry. The author included a group of mental patients into the representative groups. Besides determination of the method to be most objective and indicative in comparison with the earlier available method, there was made a conclusion that LCS allows to personify prosthesis methods by achieving optimal adjustment of dental prosthesis. There were also proved significant differences in the content of oral fluid studied in mental patients.