THE METABOLIC SYNDROME AS A FACTOR OF PRETERM BIRTH

According to the scientific studies, the incidence of preterm birth inUkraineand the world is 7–15% of the total number of births, and has no tendency to decrease. This pathology is of essential obstetric medical and social significance because of the high risk of complications both in the mother and fetus.

Objective. To determine the frequency of the metabolic syndrome in women with preterm labor.

Methods. There was made a retrospective multisample cross-sectional study of the history of pregnancy and labor in 150 women with preterm labor.

Results. The prevalence of the metabolic syndrome in pregnant women, who have had premature births, was 17.3%. The major complications of pregnancy and childbirth in this category of patients were progression of late gestosis (RR 38.2; 95% CI 9.3–155.9), premature detachment of the normally situated placenta (RR 11.9; 95% CI 2.4–58.1), fetus distress (RR 1.4; 95% CI 0.3–6.2) and premature rupture of the fetal bladder (RR 0.2; 95% CI 0.1–0.7). The majority of patients (88.5%) had Cesarean section (RR 5.2; 95% CI 3.5–7.9). Indications for operative delivery included progression of late gestosis (RR 7.3; 95% CI 1.9–28.1) and premature detachment of the normally situated placenta (RR 2.3; 95% CI 0.5–10,5).

Conclusions. The incidence of the metabolic syndrome in women with preterm labor was 17.3 %; the metabolic syndrome is a risk factor for preterm birth due to the high probability of progression of late gestosis and premature detachment of the placenta, which significantly increases the rate of operative delivery.