APPROBATION OF NEW METHODS OF OUT-MODEL ANALYSIS OF PHARMACOKINETIC TYPE OF BIOLOGICALLY ACTIVE SUBSTANCES

The results of development of new methods of out-model analysis of pharmacokinetic parameters of distributing and elimination of medicinal matters from the organism of experimental animals are represented in the article; estimation of their efficiency is given. It is shown on the basis of analysis of pharmacokinetic type of oxyethylidendiphosphonategermanates derivatives that the offered methods allow not only to estimate the processes of distributing and elimination of biologically active compounds more precisely and truthfully but also to calculate those parameters, which is not possible with the usage of available traditional methods. It promotes to improvement of pharmacokinetics researches and their cost price.