Long lasting (up to 6 month) effects of amlodipine therapy and its combination with hydrochlorothiazid (H), an perindopril (P) and carvedilol (C) were investigated in 108 patients with arterial hypertension I–III stage at out-patient phase. They evaluated the general quality of life index (QL), systolic (SBP) and diastolic blood pressure (DBP), total power (TP) and the ratio of low and high frequency (LF/HF) and M-indices of stationary variability of heart rhythm before, in an acute pharmacological test and at therapy stages.
