IMPORTANCE OF SOME PRO- AND ANTI-INFLAMMATORY CYTOKINES LEVEL FOR DIAGNOSIS OF DIABETIC RETINOPATHY

The purpose of the work was to investigate the possibility of some pro- and anti-inflammatory cytokines usage for the early diagnosis of diabetic retinopathy (DRP).

There were studied both the pro-inflammatory interleukins 1β and 6 and anti-inflammatory interleukins 4 and 10 contents in the blood in 27 patients with diabetes mellitus and 10 healthy patients.

The level of cytokines IL-4, IL-6 in patients with diabetes both with the presence of nonproliferative DRP and without it was significantly higher. Significant differences in levels of proinflammatory IL-1β and IL-10 were not found in patients with diabetes both in the presence of nonproliferative DRP and without it in healthy individuals.