INFLUENCE OF ANTIINFLAMMATORY GEL “PROFIAL” ON TUNICA MUCOSA OF MOUTH (MORPHOLOGICAL RESEARCH)

The aim of research is study of influencing “Profial” gel, including an extract Scutellaria baicalensis, on the mucous membrane of cavity of mouth of experimental rats.

Materials and methods. For conducting an experiment a model of development of inflammation of tunica mucosa of mouth, developing as a result of toxic and allergic action of methyl metacrilate, was used.

“Profial” gel action on the mucous membrane of rats was tested after applications with methylmetacrilate. The research was conducted on 30 white rats: 1st group — intact animals; the 2nd group — treatment of the mucous membrane with 1% monomer solution; 3rd group — treatment of mucous membrane by monomer + the “Profial” gel.

The mucous membrane of rats was covered with “Profial” gel after the methyl metacrilate application. Results of morphological research showed that the “Profial” gel renders irritating action and does not change mucosa structure, but after the toxic defeat of tunica mucosa of mouth restors its integrity.