BRAIN CORTEX STRUCTURAL DISTURBANCES IN EXPERIMENTAL HEMORRHAGIC STROKE

Structural and morphological changes of the rat cerebral cortex in remote period of hemorrhagic stroke were analyzed in experimental studies. Development of neurodegeneration in cortex in both hemispheres was observed in 7 months after the experimental stroke.

Studies were undertaken on 30 white laboratory rat females with mass 200–220 g. Animals were divided into 3 groups: intact, pseudooperated, animals with an experimental hemorragic stroke. The histological analysis of sections of the sensomotor neocortex pseudooperated rats allowed to set that in cerebral vessels considerable structural violations are absent after the exception of cramps of cerebral vessels. In the process of study of histological preparation of cortex of animals in 7 months after the recreation of acute stroke around separate nervous cells development of the expressed edema is marked. A number of the changed cells is marked, cells with the lysis of nuclei, more intensive colour of proximal departments of dendrites was observed.

The obtained results extend an idea about development of complications at chronic cerebral insufficiency and have an important value for development and improvement of strategies of rehabilitation of patients with a stroke.