The aim of our study was to determine the state of the inflammatory response and the relationship between the concentration of C-reactive peptide, TNF-α and IL-6 with changes in lung function and BMI in patients with hypertension. 75 patients with hypertension were examined. Anthropometric indexes were taken: height, weight, BMI. Computer spirometry was done in all patients with estimation of spirometric parameters. C-reactive peptide, TNF-a and IL-6 in blood were estimated by enzyme immunoassay analysis.
Our results suggest that obesity in hypertensive patients is associated with the increased activity of pro-inflammatory cytokines.