It was conducted the evaluation of changes of concentrations of hormones of hypophysial-adrenal and hypophysiothyroid systems at blood serum at patients with Parkinson’s disease. It is showed that at Parkinson’s disease the abnormally high secretion of corticosteroids takes place depending on the severity of course. The hypercorticoidism, in case of moderate and severe course of disease, is possible to be presented as a model of chronic stress. At Parkinson’s disease there is taking place the desynchronization of functioning of hypophysial-adrenal and hypophysial-thyroid systems, that is confirmed by increasing the corticotropin in the blood serum, hydrocortisone on a background of decreasing the thyrotrophin, thyroxin.
