COMPARATIVE EFFICACY OF LIPOFLAVON AND SOME HEPATOPROTECTORS UNDER THE EXPERIMENTAL TOXIC HEPATITIS

Toxic hepatitis was modeled by tetrachloride of carbon and alcohol in experiments on white rats of Wistar line. There was studied the comparative hepatoprotective effectiveness of lipoflavon, alpha-tocopherol, sylibor, quercetin in granules, thiotriazolin. Using advanced statistical analysis of biochemical parameters that characterize the functional status of the liver and activity of antioxidant protection it was found that lipoflavon and thiotriazolin have the most pronounced pharmacotherapeutic effect. However, therapeutic activity of alpha-tocopherol acetate and quercetin in granules in both models of toxic hepatitis was insignificant.