IFLUENCE OF EXTREMELY HIGH FREQUENCY ELECTROMAGNETIC RADIATION OF LOW INTENSITY AND DIAZEPAM ON GENERALIZED EPILEPTIC ACTIVITY

Extremely high frequency electromagnetic radiation (EHF EMR) (15,0 min) increased the latent period of appearance of first seizures and prevented appearance of generalized seizures in models of kainic acid (10.0 mcg) and benzilpenicillin (1000,0 IU intraventricularly) induced forms of epileptic syndrome. Middle-effective dozes of diazepam (ED50), which prevented kainic acid-induced tonic extension of front extremities on background of using EHF (5.0 and 15,0 min) decreased correspondingly by 38.6% and 59.1% (P<0,05). Doses (ED50) of diazepam that prevented appearance of benzilpenicillin-induced attacks of clonic convulsions on background of 5.0 and 15.0 minutes of EHF was decreased by 14.6% (P>0,05) and 48.8% (P<0,05).