N 3 (181) 2022. P. 21–25

INDICATORS OF ULTRASOUND DENSITOMETRY IN LATE REPRODUCTIVE AND PREMENOPAUSUAL WOMEN WITH DIFFERENT SOMATIC PROFILES

S. M. Korniyenko, I. V. Shpak

Odesa National Medical University, Odesa, Ukraine

DOI 10.32782/2226-2008-2022-3-4

Introduction. WHO determines that osteoporosis ranks fourth in prevalence after diseases of the cardiovascular system, oncological pathology and diabetes.

The aim of this study was to study the condition of bone tissue in women of late reproductive and premenopausal age with endometrial pathology, depending on the concomitant somatic pathology.

Materials and Methods. 90 women of late reproductive and premenopausal age with intrauterine pathology and somatic pathology were included in the study. The method of ultrasonic calcaneus densitometry, statistical data were used.

Results and Discussion. According to research data, osteopenia was detected in the sample without somatic pathology in 9.1% of cases, and among women with somatic pathology – in 38.2%. In the case of the diseases of the gastrointestinal tract osteopenia was diagnosed in 52.9% cases, in the reference sample – in 26.0% of cases, in diseases of the hepatobiliary system, the distribution was, respectively, 53.3% versus 26.7% of cases, with nephropathy in 63.6% versus 26.6% of cases, vegetative disorders in 66.7% versus in 27.2% of women.

Conclusions. Women of late reproductive and premenopausal age with the presence of somatic diseases with the background of intrauterine pathology have a decrease in densitometry indicators in the form of osteopenia. The absence of somatic diseases in women with intrauterine pathology significantly reduces the chances of osteopenia. Patients with autonomic disorders have the highest risk of developing osteopenia.

Key words: osteoporosis, densitometry, intra-uterine pathology, late reproductive age, somatic pathology.

REFERENCES

  1. Povoroznuk VV. Osteoporosis: from early diagnostics to effective treatment діагностики до ефективного лікування. Cardiology, Rheumatology, Cardiosurgery. 2019;6:25. (in Ukrainian). URL: https://health-ua.com/multimedia/userfiles/files/2019/Cardio_6_2019/Cardio_6_2019_str_24_25.pdf.
  2. Ihgatiev ОМ, PolivodaМІ, Turchyn МІ, Yermolenko ТОet al.. Clinical recommendation concerning diagnostics, prophylaxis, and treatment of osteoporosis (Klinichni rekomendatsii z diahnostyky, profilaktyky ta likuvannia osteoporozu). Herald of marine medicine (Vistnyk morskoi medytsyny). 2019; 3(84): 28–38. (in Ukrainian). URL: https://repo.odmu.edu.ua:443/xmlui/handle/123456789/6145.
  3. Borgström F, Karlsson L, Ortsäter G, Norton N. Fragility fractures in Europe: burden, management and opportunities. For the International Osteoporosis Foundation Arch Osteoporos. 2020;15(1):59.
  4. Pasiieshvili L.М. Osteoporosis – a silent osteal «thief». (Osteoporoz – bezmolvnyi kostnyi «vor») Vostochnoevropeiskyi zhurnal vnutrennei y semeinoi medytsynu. 2015;1:16-24. (in Russian).
  5. Barna OM, Korost YV, Lukianets EY. Determination of mineral density of bones in pregnant women by ultrasonic densitometry method for diagnosis of osteopenic syndrome. Medicine of Ukraine. 2019;5(231):28-33. (in Ukrainian) DOI:https://doi.org/10.37987/1997-9894.2019.5(231).186611.
  6. Dhiman P, Andersen S, Vestergaard P, et al. Does bone mineral density improve the predictive accuracy of fracture risk assessment? A prospective cohort study in Northern Denmark. BMJ Open. 2018;8:e018898. doi:10.1136/ bmjopen-2017-018898.
  7. Prevention and management of osteoporosis: report of a WHO scientific group. WHO Scientific Group on the Prevention and Management of Osteoporosis.Geneva, Switzerland. 2003. Retrieved 2007-05-31.
  8. Kim AS, Ko HJ. Atrophic Gastritis as a Risk Factor for Bone Loss in Premenopausal Women in Their 40s: A Retrospective Cohort Study. Calcif Tissue Int. 2019;104(1):34-41.
  9. Korniyenko SM. Somatic status of the patients with different forms of endometrial pathology in late reproductive age and premenopausal period. Health of woman. 2017;3(119):93-97.
  10. Pankiv ІV. Influence of thyroid functional status on the bone mineral density. Trauma. 2015;16(6):33-41. (in Ukrainian).
  11. Mirza A, Alharbi A, Marzouki H, Al-Khatib T. The Association Between Vitamin D Deficiency and Recurrent Tonsillitis: A Systematic Review and Meta-analysis. Otolaryngol Head Neck Surg. 2020;163(5):883-891.
  12. Waziri B, Duarte R, Naicker S. Chronic Kidney Disease–Mineral and Bone Disorder (CKD-MBD): Current Perspectives. Int J Nephrol Renovasc Dis. 2019;12:263-276.
  13. Muschter D, Schäfer N, Stangl H. Sympathetic neurotransmitters modulate osteoclastogenesis and osteoclast activity in the context of collagen-induced arthritis. PLoS One. 2015;10(10):1-21.
  14. Xing WM, Lv XL, Gao WY, Wang JR. Bone mineral density in patients with chronic heart failure: a meta-analysis. Clin Interv Aging. 2018;13:343-353.
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