N 1–2 (179–180) 2022. P. 43–48

CHARACTERISTICS OF PATIENTS WITH CHRONIC OBSTRUCTIVE LUNG DISEASE

N. P. Masik, T. V. Stepaniuk, O. A. Korobko, S. V. Nechyporuk

National Pirogov Memorial Medical University, Vinnytsya, Ukraine

DOI 10.54229/2226-2008-2022-1-2-8

Introduction. Calculations of the components of body mass: fat, muscle and bone serve as an objective characteristic of a person’s physique.

The aim: to evaluate the body composition indicators of patients with COPD and to establish correlational relationships.

Materials and methods. 120 patients with COPD were examined, evenly distributed by degree of severity (GOLD 1-4). Average age (56.67 ± 10.28) years. We determined: body mass index (BMI), BMD of the entire skeleton, lumbar spine (L1-L4) and radius, index of bone mineral component (BMCI), fat mass index (FMI), fat-free mass index (FFMI).

Results. The increase in FMI was established at 16.7% in GOLD 1, 33.3% in GOLD 2 and GOLD 3, and 50% in GOLD 4. Increasing severity of COPD increases the incidence of osteoporosis and osteopenia was observed, respectively: from 10.0 and 50.0 % at GOLD 1 to 50.0 and 44.3% at GOLD 4. A decrease in BMCI was detected in 16.7% of GOLD 1, 33.3% of GOLD 2, 83.3% of GOLD 3 and 100% of GOLD 4. FFMI was reduced by 11.52% in GOLD 2, by 40.09% in GOLD 3, and by 54.03% in GOLD 4 compared to GOLD 1.

Conclusions. Different phenotypes of COPD were found in the examined patients. Thus, the phenotype with obesity in 29.2% of people, the phenotype with osteopenia and osteoporosis – in 25.8% of patients, the phenotype with sarcopenia in 45.0%.

Key words: bone tissue, muscle tissue, lean tissue, sarcopenia, osteoporosis, obesity.

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