The effects of natural polyphenol parapharmaceutics (PP) originated from red brends of grape upon rats electrocorticogram (EcoG) were investigated under condition of free behaviour of animals. It was established that intraperitoneal PP administration was followed by the decreasing of amplitude of EcoG signals. Besides, directed to left-hemispheral shifting of dominance of amplitudes was noted. It was supposed that PP caused its effect via antiepileptic system activation. Also, the lateralization of effect might be in favor of pharmacological asymmetry of PP activity.
