The administration of benzilpenicillin (300,000,00 IU/100 g, i.p.) in free moving Wistar rats caused the precipitation of spikes and generalized ictal potentials with life-span of epileptic activity up to 6 h. Periodic ES of paleocerebellum (100 Hz, 1 ms, 100– 180 A duration of trial 1 s, interstimuli interval — 2.5–3.0 min) was accompanied by a significant decrease of power of epileptic activity starting at the end of the half an hour of stimulation in comparison with control rats. Besides, a reduction of the duration of epileptic activity up to 3.5 h was seen.
