Experiments on preadolescent male rats have shown that memantin administration in a dose of 10 mg/kg during 4 hours before hypoxia prevents the potentiation of peroxide oxidation of the lipids and increases antioxidant protection of the neurones in the separate brain structures. The most expressed normalization of prooxidant-antioxidant balance was registered in the frontal cortex of the large hemispheres of the brain in rats.
