Chronic stress which was induced via immobilization and electric painful stimuli delivered during four weeks was followed by the decrease of effective dosages of kainic acid and penicillin (ED50) by 41.2 and 36.4% correspondently (P<0,05). Combined usage of ketogenic diet (KD) and pentoxyphyllin (PTPh) (100,0 mg/kg i. p.) was followed by the of epileptogens ED50 increase. In case of combined usage of KD and PTPh was more pronounced than after separate effects of mentioned factors. Strong stress-protection was also seen with respect of stress-induced ulceration of the duodenum.
