Efficiency of complex treatment of acute pancreatitis and its complications in 162 patients were investigated. In 22 of them aprocal as a polivalent proteinase inhibitor, was applied. On 4th day a positive effect was marked in 45.5 % in case of aprocal application: by 53.3 % earlier, than in the control group, the peristalsis of intestine appeared, by 26.0 % — independent stool. The general mortality rate was 9.1 % against 13.6 %.
