During an experiment at white she-rats it was determined that in 20 days after HgCl2 injection in the dose of 4 mg per 1 kg of the body mass s/c during induced water and saline diuresis there are observed some pecularities of function of kidneys which manifested in decreasing tubular reabsorbtion of water and increasing proteinuria. The filtration increases at the she-rats during saline load on the 20th day of the physiologic pregnancy development. At the rats which had sublimate injection before pregnancy, there was revealed further decreasing of glomerular filtration and abilities to the osmotic dilution of the urine, and concentration of creatinine increased in the blood plasma.
